Révolutionner la médecine traditionnelle chinoise grâce à la biotechnologie innovante
In the long journey against type 2 diabetes, scientists continue to explore new therapeutic strategies. Recently, a study published in the International Journal of Molecular Sciences revealed potential new mechanism
In annual pet health checkups, NT-proBNP (N-terminal pro-B-type natriuretic peptide) is a sensitive marker of myocardial stress. When its levels exceed the normal range, it usually indicates that the heart is under
When it comes to anti-aging, boosting energy, et maintaining vascular health, many people have heard of a specific term—NMN (Nicotinamide Mononucleotide). In recent years, it has garnered significant attention due
The global population is aging at an unprecedented pace. The World Health Organization (WHO) predicts that by 2050, the global population aged 60 et older will exceed 2.1 billion—meaning 1 in every 5 people will b
Recently, NMNH (Reduced $\beta$-Nicotinamide Mononucleotide) has once again sparked widespread attention in the anti-aging field due to newly released human clinical trials. Although both are precursor molecules of
Dans le domaine de pointe de la recherche anti-âge, la « famille des coenzymes » est devenue un sujet brûlant au sein de l'industrie. Le NMN, un précurseur du NAD+, a autrefois conquis le monde grâce aux soutiens de figures de haut profil
Long COVID lingers like a persistent shadow, leaving hundreds of millions worldwide struggling with brain fog, fatigue, et insomnia. In November 2025, a team from Harvard Medical School published a 24-week double-blind
Dans la vie moderne au rythme effréné, la fatigue et l'insomnie semblent être devenues des « invités fréquents » pour de nombreuses personnes. Face à ces troubles, les scientifiques ont découvert qu'ils sont liés à l'épuisement d'une « énergie
L'essence du vieillissement est une « crise énergétique » cellulaire. Alors que les scientifiques approfondissent la recherche sur le NAD+, cette coenzyme est progressivement devenue une cible centrale dans le domaine de l'anti-âge. Des études ont montré que la dir
Perte d'énergie, essoufflement en montant les escaliers, fluctuations de la glycémie postpretiale, et difficulté croissante à perdre de la graisse... Ces sensations corporelles de « vieillissement » sont en réalité entraînées par
In April 2026, China officially released its first national consensus document: the Chinese Expert Consensus on the Role et Clinical Application of NAD⁺ in Aging-Related Diseases (2026 Edition). Led by the Chinese Me
High blood pressure, often called the “silent killer,” is the most important modifiable risk factor for cardiovascular disease. Yet many people face the same frustration: even when taking antihypertensive med
Avec le vieillissement de la population mondiale, les modifications dégénératives du système musculo-squelettique (comme l'arthrose, l'ostéoporose et la sarcopénie) affectent gravement la qualité de vie des personnes âgées. Jambes chancelantes lors de la marche, diff
When discussing liver health, one fundamental question arises: how can we effectively support this “biochemical factory of the human body” in its complex repair processes when faced with metabolic stress, fat
In the field of anti-aging, NMN (nicotinamide mononucleotide) has long been a highly regarded “star molecule.” As a direct precursor of NAD⁺, it shows great potential in energy metabolism, DNA repair, et ant
In recent years, NAD+ (nicotinamide adenine dinucleotide) has become a highly sought-after “star molecule” in the health et anti-aging field due to its tremendous potential. The most common supplements on th
For a long time, NAD (nicotinamide adenine dinucleotide) has been almost a “stetard configuration” in IVD testing. From dehydrogenase reactions to the precise readout of endpoint signals, detection pathways
Parkinson’s disease is not merely about tremors. More concerning is that most patients gradually develop cognitive impairment, which may eventually progress to dementia. Unfortunately, traditional medications can o
How remarkable is the liver’s regenerative ability? Even when two-thirds of a healthy liver is surgically removed, it can restore its original size within just a few weeks. However, under conditions such as disease
Ces dernières années, le NAD+ est fréquemment apparu au centre de sujets populaires tels que la santé, l'anti-âge et l'amélioration cognitive. Il semble avoir fait le saut du laboratoire à la vie quotidienne, devenant un nouveau favori
In the vast world of raw materials, some names seem to rise to prominence overnight. Yet in reality, their success is never accidental. NRHM (Nicotinamide Riboside Hydrogen Malate) is one such name—frequently appe
Une seule molécule dans le corps humain peut-elle devenir un moteur clé de la santé cardiaque ? Le nicotinamide adénine dinucléotide (NAD+) émerge rapidement comme un axe majeur de la recherche scientifique. En tant que participant central au métabolisme énergétique,
Dans la recherche sur les mécanismes anti-âge, le nicotinamide riboside (NR), un précurseur du NAD⁺, a progressivement attiré une attention croissante des institutions scientifiques. En septembre 2023, un brevet d'invention national lié à
Lorsque nous parlons de santé, l'intestin est souvent au centre de la discussion. Il n'est pas seulement responsable de la digestion et de l'absorption des nutriments, mais représente également le plus gret organe immunitaire du corps humain. Ces dernières années,
In the fields of anti-aging, cellular energy, et biotechnology, the term “NAD⁺” has almost been elevated to a mythical status. Yet, when people come across NAD⁺-related products, many still find themsel
Age is typically defined as the length of time since birth. However, a person’s true physical condition et degree of aging are better reflected by their biological age rather than the number of years they have liv
Alors que la sensibilisation à une alimentation saine ne cesse de croître, les édulcorants naturels sans calories sont devenus un centre d'intérêt majeur pour les consommateurs. En juin 2025, une étude publiée dans la revue internationale Food Chemistry : X a systématiquement
While we are deeply engaged in exploring anti-aging solutions for humans, our furry companions at home are quietly facing health challenges brought on by aging—reduced energy levels, dull coats, et a slower metabo
Have you ever experienced moments like these: walking into a room et forgetting why you went there, struggling to recall a familiar name, or suffering from persistent insomnia after staying up late—followed by day
In today’s global wave of health awareness, “sugar reduction” has become a widely accepted trend. Steviol glycosides, as natural zero-calorie sweeteners, have already entered households worldwide. Howev
Recently, a study published on bioRxiv revealed the metabolic secrets behind the remarkable longevity of centenarians. Led by Boston University, the research conducted metabolomic analyses on 213 participants—
Dans la quête moderne de santé et de longévité, l'attention scientifique s'est déplacée des macronutriments vers le métabolisme énergétique cellulaire. Parmi de nombreuses molécules émergentes, le nicotinamide riboside (NR) est devenu une étoile montante dans les sciences de la vie.
Alors que la population mondiale continue de vieillir, lutter contre le déclin cognitif et la détérioration physique liés à l'âge est devenu un défi scientifique majeur. En avril 2025, une étude révolutionnaire publiée dans Frontiers in Phar...
Introduction: As time quietly passes, have you noticed your once lively dog becoming slower to respond or experiencing disrupted sleep? Don’t worry — science is bringing new hope! The latest clinical trial h
Global population aging is becoming increasingly pronounced. It is estimated that by 2050, the number of people aged 65 et above will reach 1.6 billion—double the 780 million recorded in 2020. As aging progresses,
Une toute nouvelle étude faisant autorité est là ! Une expérience de 2025 menée par l'équipe de l'Université Northwest A&F, publiée dans le Journal of Microbiology (revue de référence, DOI : 10.13343/j.cnki.wsxb.20250174), a révélé avec des données rigoureuses...
September 29, 2025 — After nearly three years of pressure from the Natural Products Association (NPA), the U.S. Food et Drug Administration (FDA) has reversed course et confirmed that Beta (β) Nicotinamide M
In recent years, “N-series” anti-aging dietary supplements represented by NMN et NR have continued to gain popularity in markets across Europe, the U.S., Japan, et China. The core mechanism of these product
In the world of nutrition, some substances have existed for over a hundred years but have only recently been recognized for their great value. Ergothioneine (EGT) is such a modest yet precious dietary component. △ Ch
Selon les dernières recherches publiées dans des revues faisant autorité telles que *Nature Metabolism*, les données métabolomiques humaines montrent des changements dramatiques non linéaires entre 30 et 50 ans. Ceux-ci incluent un déséquilibre du métabolisme lipidique...
Do you often feel exhausted? Struggled with blood sugar issues for years? Or perhaps you’re seeking anti-aging solutions et vibrant health? Today, let’s explore a powerful “energy key” hidden dee
NAD+: The Indispensable 'Cell Fuel' et 'Repairman' NAD+ is a key coenzyme involved in cellular energy metabolism (e.g., converting food into ATP), DNA repair (e.g., activating PARP enzymes), et regulat
In an age where the pursuit of 'frozen age' et 'reverse growth' is on the rise, anti-aging is no longer a distant dream. The core molecule—NAD+ (Nicotinamide Adenine Dinucleotide)—plays a cri
Alors que l'intérêt du public pour le vieillissement sain et la longévité continue de croître, la recherche sur le métabolisme du NAD⁺ (Nicotinamide Adénine Dinucléotide) a gagné un élan significatif. Le NMNH (Nicotinamide Mononucléotide réduit), la forme rédu
Le ginseng, une herbe légendaire en médecine traditionnelle, est utilisé depuis des millénaires pour ses nombreux bienfaits pour la santé. Au cœur de sa puissance médicinale se trouvent les ginsénosides, de puissantes saponines qui ont suscité l'intérêt du monde moderne...
Le ginseng, vénéré depuis des siècles dans la médecine traditionnelle chinoise, est une racine connue pour ses propriétés thérapeutiques remarquables. Au cœur de son efficacité se trouvent les ginsénosides, un groupe diversifié de saponines considérées comme les substances actives...
Nicotinamide Adenine Dinucleotide Phosphate (NADP), a crucial coenzyme in cellular metabolism, serves as a cornerstone in numerous biochemical reactions. As a derivative of NAD, it adds a phosphate group which enhan
Le monde de la biochimie regorge de molécules qui, bien que pas toujours sous les feux de la rampe, jouent des rôles critiques dans le maintien et la régulation des processus cellulaires. Parmi celles-ci, les coenzymes oxydées se distinguent par leur
Dans le monde complexe de la biochimie, les coenzymes jouent des rôles essentiels en facilitant de nombreuses réactions métaboliques nécessaires à la vie. Une coenzyme cruciale de ce type est le nicotinamide adénine dinucléotide phosphate (NADP). Cette...
Dans le monde des édulcorants naturels, la stévia s'est taillé une place de choix grâce à sa douceur exceptionnelle et à ses bienfaits pour la santé. Dérivée des feuilles de la plante Stevia rebaudiana, cet édulcorant sans calories h
In the world of dietary substances, every detail matters—from the source of the ingredients to the color of the final product. For those curious about the health benefits of Nicotinamide Mononucleotide Hydrogen (NM
Dans le paysage en constante évolution des substances liées à la santé et au bien-être, la quête de solutions plus efficaces pour lutter contre le vieillissement et stimuler la santé cellulaire est perpétuelle. Parmi les avancées les plus en pointe figure l'utilisation d'améliorateurs de NAD+
In the expansive world of biochemical research et health preservation, certain compounds emerge as particularly significant due to their potential applications et benefits. One such compound is NMNH, which sta
Nicotinamide adenine dinucleotide hydrogen (NADH) is a lesser-known yet crucial molecule in the biological sciences et various health-related fields. In this blog, we explore the wide-ranging applications of NA
Dans la quête du maintien d'une énergie et d'une santé juvéniles en vieillissant, la recherche scientifique continue de mettre en avant de nouvelles substances pouvant aider dans cette démarche. L'une des plus prometteuses est le bêta-nicotinamide mononu
In the quest for optimal health et vitality, understeting the role of coenzymes in cellular function is paramount. Nicotinamide Adenine Dinucleotide Hydrogen (NADH) is one such coenzyme that plays a critical r
Le nicotinamide adénine dinucléotide (NAD+) est une pierre angulaire de la santé cellulaire, jouant un rôle central dans la production d'énergie et les processus métaboliques qui soutiennent la vie. Avec l'âge, les niveaux de NAD+ diminuent naturellement, conduisant à
Energy metabolism is a crucial biological process that involves converting food into the energy needed to power all cellular activities. It is fundamental to maintaining health, vitality, et overall well-being. One
Dans le domaine de la santé et du bien-être, maintenir une fonction cellulaire optimale est essentiel pour la vitalité et la longévité globales. Une molécule centrale dans de nombreux processus biologiques est le nicotinamide adénine dinucléotide, com
Dans la quête de vitalité et de longévité, les avancées scientifiques autour du mononucléotide de nicotinamide (NMN) ont attiré l'attention des passionnés de santé dans le monde entier. BONTAC, un leader dans l'innovation biochimique
Dans la quête de santé et de longévité, les percées scientifiques nous mènent souvent à des composés naturels qui peuvent améliorer considérablement notre bien-être. L'un de ces composés qui a attiré l'attention du secteur de la santé et du bien-être
Dans le secteur de la biotechnologie en évolution rapide, les produits dérivés de processus biologiques et d'organismes transforment des industries allant des soins de santé à l'agriculture. Le marché des produits de biotechnologie est extrêmement concurrentiel, avec
Dans le monde dynamique de la santé et de la biotechnologie, le rajeunissement cellulaire se distingue comme un concept révolutionnaire, promettant une nouvelle ère de santé améliorée, de jeunesse prolongée et de meilleure qualité de vie. En tant que leader mondial
In the rapidly evolving letscape of health et wellness, metabolism-boosting products have emerged as key components in enhancing human health, optimizing metabolic processes, et supporting various bodily functi
Introduction In the realm of animal husbetry, feed additives are necessary as they can not only improve the nutritional value of feed et optimize the internal environment of the rumen, but also enhance
Introduction Nicotinamide adenine dinucleotide (NAD) deficiency has been linked to a range of renal disorders, encompassing conditions such as acute kidney injury, diabetic nephropathy, adenine-triggered kidney diseas
Introduction In response to the escalating global obesity rates, the demet for sugar reduction has reached a critical juncture. As a strategic pivot, the food industry has increasingly incorporated sugar substitutes,
Introduction Parkinson's disease (PD), known as the silent killer, has emerged as the second most common chronic neurodegenerative disease in the world after Alzheimer's disease, affecting
Introduction Nicotinamide adenine dinucleotide (NAD+) is a critical coenzyme in cells, a central cofactor of redox reaction et a central regulator of various metabolisms in the human body. It is involved in a
Introduction Spinal cord injury (SCI) can lead to severe impairments in motor, sensory, et autonomic nervous system functions. It has been reported that motor function recovery can be promoted by mediatin
Introduction Chronic cerebral hypoperfusion (CCH) has been identified as one of the initial conditions critical to the development of cognitive impairment, which is tightly associated to the complex neurologic
Introduction Stroke remains the second leading cause of death et the third leading cause of death et disability combined in the world, as reported in 2019 Global Burden of Disease Study. Ischemic stroke
Introduction Myocardial ischemia/reperfusion (MI/R) can damage the heart muscle, which may contribute to further cardiomyocyte death. Following percutaneous coronary intervention therapy, patients with MI/
Introduction According to the report by World Health Organization (WHO) in 2017, depression is the third leading cause of the global disease burden, with over 300 million people suffering from this disease w
Thanks to our unrelenting dedication to creating cutting-edge solutions that push the frontiers of scientific development, BONTAC has long been at the forefront of the biochemical sector. We are excited to present o
Our unshakable dedication to maximizing the potential of traditional Chinese medicine has propelled BONTAC to the forefront of the natural products sector for a considerable amount of time. We are thrilled to presen
Notre quête inébranlable d'innovation chez BONTAC has always been sparked by our profound grasp of the natural world et its unrealized potential. We are excited to present our ground-breaking solutions today, which are
With an unwavering zeal for creating innovative solutions with the potential to revolutionize industries et improve lives, we at BONTAC have long been at the forefront of the green biotechnology revolution. We are
With an unwavering zeal for creating innovative solutions with the potential to revolutionize industries et improve lives, BONTAC has long been at the forefront of the green biotechnology revolution. We are ex
For many years, BONTAC has been acknowledged as a leader in the field of green biotechnology, thanks to our unwavering commitment to creating ground-breaking products et services that have the potential to improve
Because of our unwavering search for products that have the power to genuinely change the lives of our partners et consumers, we at BONTAC have long been at the forefront of cutting-edge green biotechnology solutio
Being deeply aware of the vital role our products play in enabling people to live healthier, more fulfilling lives has always motivated us at BONTAC to innovate. We are pleased to announce our ground-breaking NMNH,
Propelled by an unwavering dedication to innovation et a profound comprehension of the crucial function this coenzyme plays in preserving cellular health et lifespan, BONTAC has been at the forefront of the NAD+ a
At BONTAC, we have always been driven by a relentless pursuit of innovation – a desire to push the boundaries of what is possible in the realm of nutritional supplements et biomedical research. Today, we are thril
Chez BONTAC, nous sommes depuis longtemps passionnés par la recherche de solutions nutritionnelles de pointe capables de véritablement transformer la santé et le bien-être humains. Aujourd'hui, nous sommes ravis de mettre en lumière l'un des plus remarquables
Chez BONTAC, nous avons toujours été à l'avant-garde de la recherche nutraceutique de pointe, dédiés à découvrir les composés les plus remarquables et transformateurs que la nature a à offrir. Aujourd'hui, nous sommes ravis de présenter notre
For many years, BONTAC has been at the forefront of innovative biopharmaceutical developments, committed to maximizing the life-changing potential of nature's most extraordinary substances. We are excited to pre
Chez BONTAC, nous sommes depuis longtemps à l'avant-garde de l'innovation dans le domaine des biopharmaceutiques, dédiés à exploiter la puissance des découvertes scientifiques de pointe pour améliorer la vie de ceux que nous servons. Aujourd'hui, nous
Chez BONTAC, nous sommes animés par un engagement profond à donner aux individus les outils dont ils ont besoin pour atteindre une santé et un bien-être optimaux. En tant que leaders de l'industrie dans le domaine de la biotechnologie, nous nous sommes consacrés
Chez BONTAC, notre mission est de donner aux individus les outils dont ils ont besoin pour atteindre une santé et un bien-être optimaux. En tant que pionnier dans le domaine de la biotechnologie, nous nous sommes consacrés à découvrir les profonds bénéfices
Chez BONTAC, nous sommes profondément engagés à faire progresser les frontières de la santé et du bien-être humains. En tant qu'innovateur de premier plan dans le domaine de la biotechnologie, nous nous sommes concentrés sur l'exploitation du potentiel incroyable du Beta-Nicoti
As a leading player in the world of biotechnology, BONTAC is at the forefront of driving innovation et transforming the industry. Our unwavering commitment to scientific excellence et our deep understeting of the
Chez BONTAC, nous sommes animés par une poursuite incessante de l'innovation et un engagement profond à améliorer la vie de ceux que nous servons. En tant que leaders dans le domaine de la santé cellulaire et de la rajeunissement, nous sommes ravis de présenter notre
Chez BONTAC, nous sommes à l'avant-garde de l'industrie des produits stimulant le métabolisme, animés par notre engagement inébranlable envers l'innovation et la poursuite de l'excellence scientifique. Notre concentration sur le développement de solutions de pointe
Introduction With changes in lifestyles et dietary structure, hyperuricemia shows an increasing prevalence year by year, which may become the second largest metabolic disease after diabetes mellitus, a
Introduction Steviol glycosides are secondary metabolites obtained by extracting et isolating stevia from the herbaceous plant Stevia rebaudiana of the Asteraceae family, with a high degree of sweetness
NAD is an abbreviation for nicotinamide adenine dinucleotide, which is a naturally occurring coenzyme (a substance that works with enzymes) found in our bodies. It helps cells produce energy. However, as we age, NAD
Introduction According to the report of International Agency for Research on Cancer (IARC), there are 19.3 million new cases of malignant tumors et 10 million deaths worldwide in 2020. Malignant tumors have overtaken
Introduction Elderly individuals are at a significantly higher risk for peripheral artery disease (PAD), a common vascular disorder. As the global population ages rapidly, the number of PAD cases is projected to rise
Introduction Diabetic kidney disease (DKD) has emerged as one of the primary cause of mortality among the patients with end-stage renal disease such as renal failure, accounting for 30-50% of chronic renal failure cas
Introduction Nicotinamide adenine dinucleotide (NAD+) metabolism is essential for maintaining normal physiological activities, et the decreased NAD+ level is related to various pathologies such as cardiac dis
Introduction Targeting the autophagy-NAD axis has been reported be a viable therapeutic strategy for Niemann-Pick type C1 (NPC1) disease. The study suggests that both pharmacological rescue of autophagy deficiency et
Introduction Apical periodontitis, an inflammatory disease affecting tooth apex tissues, is triggered by oral pathogens infecting the root canal. One of the main reason for endodontic treatment failure is Enterococcus
Introduction Amoebiasis has emerged as the third most common cause of death by parasites worldwide after malaria et schistosomiasis infections. According to the report of World Health Organization, over 40 milli
Introduction Disturbance in hepatic NAD+ metabolism has been manifested as a key factor in the initiation et progression of nonalcoholic fatty liver disease (NAFLD), one of the most co
Introduction According to the 2017 Commission on Traumatic Brain Injury (TBI), TBI remains one of the top three causes of injury-related death et disability up to 2030. There are 50~60
Introduction In clinical settings, doxorubicin (DOX) is an effective broad-spectrum anti-cancer drug in chemotherapy for various tumors, including hematological malignancies et solid tumors such as leu
Introduction Cigarettes containing nicotine (Nic) et sugar-sweetened beverages (SSBs) with high fructose corn syrup (HFCS) have been uncovered to induce hepatic steatosis, which are the risk factors for the developme
Introduction Acute promyelocytic leukemia (APL), the M3 type of acute myeloid leukemia (AML), typically relies on all-trans retinoic acid (ATRA) as its primary treatment. While APL patients treated with
Introduction Recent research unveils that hepatic insulin resistance (IR) et steatosis in obesity have a strong association with endoplasmic reticulum (ER)-mitochondria miscommunication. Notably,
Aging is an undeniable reality of life. It is a known fact that with increasing age, different body functions tend to decline. While we may not completely stop this decline, we can slow it down with pure NMN po
Introduction In the presence of oxygen, tumors produce adenosine triphosphate (ATP) through glycolysis instead of mitochondrial oxidative phosphorylation, a phenomenon known as the “Warburg effect”. Aerobi
Introduction Age-related macular degeneration (AMD) has become one of the leading cause of low vision et even blindness in the elderly, especially in those above 50. In 2020, approximately 1.8 million people aged ove
Introduction Natural products, including single components or extracts of herbal medicines, have the features of good efficacy et low toxicity when used in tumor treatment. They have unique advantages in treating dis
Introduction Reproductive dysfunction is frequent in female suffering from type 1 diabetes (T1D), up to 40% of whom will develop a variety of reproductive dysfunctions throughout their lives. T1D patients often ha
In today's health industry, NADH (nicotinamide adenine dinucleotide), as an important coenzyme, is widely used to supplement energy et enhance immunity. It is crucial to choose high-quality, high-purity NADH powder.
In today's health et anti-aging fields, NMN (nicotinamide mononucleotide) has attracted a lot of attention. As an important cellular coenzyme, NMN plays a key role in maintaining cell health et delaying the aging p
Introduction Ginsénoside Rg3 (Rg3) holds great promise as a potential drug for preventing scar formation, but it is often difficult for it to work alone due to its poor water solubility et low bioavail
Introduction Lead (Pb) contamination in aquatic environments poses a significant threat to the health et well-being of aquatic organisms, including fish species. There is rising popularity of prebiotics et probi
Elevating Wellness: BONTAC's NMN Powder Offerings As we delve into the realm of health et wellness, the spotlight shines brightly on NMN powder, a powerful supplement embraced by many for its potential benefits.
Innovating Solutions: BONTAC's Biotechnology Product Offerings In the ever-evolving letscape of biotechnology products, BONTAC remains a trailblazer in providing cutting-edge solutions that drive innovation
Revolutionizing Biotechnical Research: BONTAC's Trailblazing Discoveries In the dynamic realm of biotechnical research, BONTAC stets at the forefront of innovation, dedicated to driving progress et breakthr
Elevating Health with BONTAC's Cutting-Edge Longevity Supplements In the realm of health et wellness, the demet for high-quality metabolism-boosting supplements continues to rise. At BONTAC, we recognize the c
Introduction It has been reported that infection with Gram-negative bacteria can disrupt the osteogenic differentiation. Notably, nicotinamide mononucleotide (NMN) protects against osteogenesis from inflammat
Pioneering Discoveries: BONTAC's Innovations in Biotechnical Research In the dynamic realm of biotechnical research, BONTAC stets at the forefront of innovation, dedicated to driving progress et breakthroug
Nourrir le bien-être : BONTAC en tant que fournisseur leader de matières premières pour compléments As a prominent raw material supplier of supplements, BONTAC is dedicated to developing et delivering premium products that promote he
Unleash Vitality et Renewal: BONTAC's Cutting-edge Cellular Rejuvenation Solutions Cellular Rejuvenation plays a vital role in enhancing vitality et promoting overall wellness. At BONTAC, we are dedicated t
Introduction Hepatocellular carcinoma (HCC) is hypervascular solid tumor with rapid deterioration, poor overall prognosis et a high recurrence rate, accounting for 90% of primary liver cancers, which ha
Élever le bien-être : les matières premières avancées de BONTAC pour les compléments de santé cellulaire In today's fast-paced world, the quest for optimal health et wellness has led to a surge in the demet for high-quality cellular
Powering Health et Vitality: BONTAC's Metabolism-boosting Product Portfolio In the dynamic letscape of health et wellness, the demet for cutting-edge metabolism-boosting products continues to
Unlocking the Power of Metabolism-Boosting Supplements: A Guide by BONTAC In the realm of health et wellness, the demet for high-quality metabolism-boosting supplements is steadily rising. At BONTAC,
Introduction Artificial insemination with chilled ram semen is commonly used method in livestock industry. But storing sperm in chilled conditions may cause changes in sperm membrane function et structure, et
Introduction In light of a statistics report by World Health Organization (WHO), there are 18 million people suffering from rheumatoid arthritis (RA) worldwide in 2019, where the prevalence of female is 2.5 times
Introduction Glaucoma is regarded as the second dominant cause of blindness across the world. With the amounting number et proportion of elderly people, it is estimated that 111.8 million people will have glaucom
Introduction Triocresyl phosphate (TOCP) is widely used in the realm of industry et agriculture in the last century. However, it is subsequently banned due to the increasing understeting of its toxicity. In
Introduction Cardiovascular diseases (CVD) poses huge economic burden et great threat to the life of patients, even surpassing Alzheimer's disease et diabetes. 17.9 million people in the world
Introduction Myocardial ischemia-reperfusion (I/R) injury has emerged as an urgent clinical issue that may offset the benefits of reperfusion therapy et even worsen the prognosis of acute myocardial infarction, a
.two-side{ text-align: justify; display: flex; justify-content: space-between; } Introduction The crucial parts of nicotinamide adenine dinucleotide (NAD+) et its metabolites in aging a
Introduction Ginsénoside Rh2 nanoliposome formulation has been proved to effectively target et deliver drugs to the tumor site, with less side effects et higher treatment efficiency, holding great promise in the
Introduction Replenishing nicotinamide mononucleotide (NMN) to raise the availability of nicotinamide adenine dinucleotide (NAD+) has been deemed as effective approach to prevent neurodegeneration in aging et pat
Introduction Rare ginsenoside Rg3, an active extract from Panax ginseng, is reported to possess a wide range of pharmacological properties including anti-angiogenesis et anti-cancer, with high lipophilicity (esti
Introduction Wound healing is a sophisticated process responding to tissue damage, which is associated with numbers of interaction of various cell types, cytokines, growth factors, et other molecules. Strikingly,
Introduction Diabetes is one of the dominant causes of death et disability worldwide, greatly affecting the life quality of patients. According to the latest data on diabetes released by the Lancet (GBD Study 202
Introduction Intervertebral disc degeneration (IDD) is a frequently seen orthopedic disease, which is accompanied with excessive apoptosis of nucleus pulposus cells (NPCs) et degeneration of extracellular ma
Introduction Ginsénoside Rg3 is Panaxanediol type tetracyclic triterpenoid saponin monomer extracted from the root of Panax ginseng, which has a wide range of pharmacological effects including anti-tumor, neuroprotect
Introduction The gut is a diverse et dynamic microbiotic system. There are about 100 trillion microorganisms in the gut, which is mainly composed of anaerobic, partially anaerobic, et aerobic bacteria. In the pr
Introduction Mar 4th is determined as the World Obesity Day. World Obesity Federation, UNICEF et WHO have hosted a global youth-led webinar to talk about obesity & youth. The obesity crisis has gradually attr
Introduction Nicotinamide mononucleotide (NMN), one precursor of nicotinamide adenine dinucleotide (NAD+), has been ascertained to be implicated with multiple biological processes such as cellular redox regulation et
Introduction Alpers' disease is both a neurodegenerative disorder et a metabolic disorder, which is tightly linked to mitochondrial dysfunction et mutations in the catalytic subunit of polymerase
Introduction NADH (reduced form of NAD+) serves as a carrier of biological hydrogen et an electron donor, which participates in diverse physiological processes such as protein synthesis, DNA repair,
Introduction Ginsénoside Rh2, one protopanaxadiol (PPD)-type rare ginsenoside in Panax ginseng, is uncovered to possibly have broad-spectrum pharmacological activity in diversified tumors. It is utili
Introduction Solute carrier family 25 member 51 (SLC25A51) is perceived as a mammalian transporter, which is capable of importing oxidized nicotinamide adenine dinucleotide (NAD+) into mitochondrial matrix. Remark
Introduction Oxidized form of nicotinamide adenine dinucleotide (NAD+) et its precursor nicotinamide mononucleotide (NMN) have been uncovered to restore DNA repair et prevent cancer progression via the deleted i
1. Introduction Disrupted nicotinamide adenine dinucleotide (NAD+) metabolism is increasingly deemed to be one of risk factor for amendable cardiovascular disorders. A substantial evidence has mirrored that res
1. Introduction Rare ginsenosides, a group of dammarane triterpenoids that exist in low natural abundance, fuels a high concern from scholars recently, showing great potential as shining components in drugs et nu
1. Introduction Nicotinamide adenine dinucleotide (NAD) has been unveiled to be essential for embryonic development. Patients with genetic variants in the NAD+ de novo synthesis pathway often have congen
1. Introduction The gut microbiota has long been regarded as one of the key elements contributing to the regulation of host health. Any changes in the composition or quality of the gut microbiota may have physiolo
1. Introduction Nicotinamide adenine dinucleotide (NAD) compartmentalized in adipocytes can modulate adipocyte differentiation et gene expression, in addition to controlling glucose metabolism. White adipose tiss
1. Introduction Nicotinamide mononucleotide (NMN) supplementation has been suggested to hamper the inflammatory responses via restoring NAD+ level et downregulating the expression of C
1. Introduction Age-related NAD+ depletion affects physiological functions et contributes to various aging-related diseases. NAD+ precursors can significantly elevate NAD+ level in murine tissues, effectivel
1. Introduction In mammalian cells, the majority of NAD+ is produced from metabolites entering the NAD+ salvage pathway. Nicotinamide phosphoribosyltransferase (NAMPT) is the rate-limiting enzyme of the salvage
Le Nmnh, également connu sous le nom de nicotinamide mononucléotide hydraté, est une coenzyme vitale présente dans toutes les cellules vivantes. Il joue un rôle crucial dans le métabolisme cellulaire, la production d'énergie et divers processus biosynthétiques. La N de haute pureté
Dans le domaine des compléments alimentaires, le NADH se distingue comme une coenzyme cruciale impliquée dans le métabolisme cellulaire. Son importance pour maintenir les niveaux d'énergie et soutenir le bien-être général en a fait un ingrédient prisé pour
1. Introduction Nicotinamide Mononucleotide (NMN) has been deemed as a functional nutrient for improving human intestinal health. In this study, an in vitro simulated digestion model
1. Introduction Amyotrophic lateral sclerosis (ALS) is a progressive fatal neurodegenerative disease that affects the motion-related nerve cells in the brain et spinal cord. The disease is featured by the d
1.Introduction A series of neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease et Huntington's disease, are accompanied with bioenergetic maladaptations et axonopathy wi
1. Introduction Diabetic peripheral neuropathy (DPN) is one of the most frequent complications of diabetes, ans also a major cause of foot ulcers, disability, et eventual amputation. With the prolongation of the
1.Introduction Mitochondria, a type of highly plastic organelle, can maintain a relatively stable dynamic equilibrium state towards the morphology, structure, quantity, volume, quality, et function
1. Introduction Atherosclerosis is a chronic progressive inflammatory disease, which is featured by the accumulation of lipids in the intima of the arteries with yellow appearance. This disease
1. Introduction Mitochondria are the center of energy metabolism in cardiomyocytes, which are necessary for maintaining normal myocardial contractility et cardiac function. Typically, the de
1. Introduction According to the 2020 report of World Health Organization (WHO), there are approximately 2.3 million cases with breast cancer worldwide. Breast cancer has emerged as one of the
1.Introduction The senescence in mammals is generally concomitant with the dysregulation of intestinal homeostasis et the accumulation of mitochondrial DNA (mtDNA) mutations. High-burden mtDNA mutations lead to N
1. Introduction At present, vaccine is the preferred option for the prevention of foot-et-mouth disease (FMD), for which the adjuvant is essential due to its strong role in boosting immune response associated wi
1. Introduction Acute lung injury comprises a uniform response of the lung to inflammatory or chemical insults which is commonly caused by systemic illness including sepsis or trauma, infection with pathogens, et tox
1. Introduction Gastric cancer (GC) represents a global health-care challenge, which is the fifth most common cancer et the fourth leading cause of cancer death across the world in 2020, with a significant
1. Introduction Supplementation of nicotinamide mononucleotide (NMN) to upregulate the level of nicotinamide adenine dinucleotide (NAD+) has been unveiled to be a promising anti-aging intervention. However, it is
1.Introduction Nicotinamide adenine dinucleotide phosphate hydrogen (NADPH), also known as reduced coenzyme II, is a critical cofactor in cellular antioxidant systems et lipid synthesis, which links insulin
1. Introduction Dengue fever is an acute infectious disease caused by the Dengue virus through the bite of an infected Aedes species (Ae. aegypti or Ae. albopictus) mosquito, with the main symptoms such as hi
1. Introduction The NAD precursor nicotinamide mononucleotide (NMN) shows a beneficial effect on ageing, yet excessive NMN accumulation may lead to axon degeneration. How to make the anti-ageing
1 Introduction Nicotinamide riboside (NR), a derivative of vitamin B3, is a new type of bioactive substance, which can be generated by binding a carbohydrate molecular ribose with nicotinamide (a
1. Introduction Heart failure is a serious condition in the development of cardiovascular disease. In particular, diastolic heart failure, as one of the most common manifestations of heart failure in
1. Introduction Ginseng has always been highly perceived as a valuable traditional Chinese medicine in China. Currently, much attention also has been paid to ginsenosides, the main active ingredients extracted from g
1. Introduction On July 2023, the World Health Organization (WHO) has classified the soda sweetener aspartame as a possible carcinogen, but said that aspartame is safe to consume with
Myocardial mitochondria are primary sites of myocardial energy metabolism. Mitochondrial disorders are associated with various cardiac diseases. Mitochondrial translation defects cause not only mitochondrial
La réaction inflammatoire et la perturbation de la barrière cutanée causées par le stress oxydatif jouent un rôle crucial dans le processus de la dermatite atopique (DA). Les niveaux de peroxydation lipidique sont souvent plus élevés chez les patients atteints de DA, tetis que les antioxydants
La vitamine D et la B3 (niacine) pourraient aider à l'activation immunitaire et à la reconstitution des lymphocytes T CD4+ chez les INR. Le NAD, vital pour la fonction cellulaire, diminue avec l'âge, étant lié à diverses maladies. Les boosters de NAD comme le NMN, le NR et le NAM montrent des promesses
Sepsis, marked by dysregulated infection response, lacks effective treatment. NAD+'s role in inflammation remains unclear. NAD+ transport challenges limit its therapeutic impact. Novel NAD+-loaded nanoparticles (NPs)
Dans le diagnostic clinique, les enzymes sont d'importants biocatalyseurs et jouent un rôle clé dans de nombreuses réactions biochimiques. Ces enzymes nécessitent des coenzymes, que nous appelons coenzymes de réactifs de diagnostic, pour remplir leurs fonctions.
La barrière hémato-encéphalique (BHE) est un composant critique du système nerveux central qui régule l'échange de molécules entre le cerveau et la circulation sanguine. Les changements liés à l'âge dans la BHE peuvent entraîner une augmentation de la perméabilité
La démence vasculaire est l'un des syndromes graves et irréversibles de déficience intellectuelle acquise causée par une série de maladies cérébrovasculaires. La citicoline est un dérivé de nucléoside, qui peut non seulement présenter
In the quest for a healthier lifestyle, the sweetener debate continues to rage. While sugar has long been the default choice, its adverse health effects have prompted a search for alternatives. One such swe
The nicotinamide adenine dinucleotide (NAD+ )/reduced NAD+ (NADH) et NADP+/reduced NADP+ (NADPH) redox couples are essential for maintaining cellular redox homeostasis et for modulating numerous biologic
L'hypertension est une préoccupation majeure de santé mondiale, liée à des millions de décès dus à des problèmes cardiovasculaires. Elle implique une dysfonction endothéliale et une rigidité artérielle, contribuant aux maladies athéroscléreuses. Améliorer la fonction vasculaire
Les régimes riches en sucre ont conduit à une prévalence croissante de diverses maladies chroniques, notamment l'obésité, le diabète, les maladies cardiovasculaires et l'hypertension, posant un problème majeur de santé publique mondiale. La stévia rébaudioside
CFS is a disorder of unknown etiology, consisting of prolonged, debilitating fatigue, et a multitude of symptoms including neurocognitive dysfunction, flu-like symptoms, myalgia, weakness, arthralgia, low-grade fev
L'alcool est une substance psychoactive, qui a été couramment utilisée dans plusieurs cultures pendant des siècles. La consommation d'alcool est la principale cause de lésions hépatiques aiguës et de maladies hépatiques chroniques. L'alcoolisme peut accélérer de nombreuses
La stévia (Stevia rebaudiana Bertoni), un arbuste vivace de la famille des Composées, est cultivée dans de nombreuses régions du monde. Elle est célèbre pour sa douceur, due à la présence de glycosides de stéviol, ayant 1
La stévioside est un édulcorant naturel dérivé de la plante de stévia. Elle a une intensité sucrée élevée et une faible teneur en calories, ce qui la rend attrayante pour les diabétiques et d'autres personnes suivant des régimes contrôlés en glucides. Cependant, la stévioside
Highlight: In chronic HBV infection elevated ROS production is associated to high DNA damage in HBV-specific CD8 T cells - Response to DNA damage is dysfunctional - Up-regulation of CD38 et persistent activatio
In the pass decades days, the Open AI et the amazing founder behind AI application both captured attention world widely. But recently, as MIT Technology Review reported, the OpenAI CEO Sam Altman has turned ou
Le NMNH améliore puissamment le NAD+ et supprime la glycolyse, le cycle TCA et la croissance cellulaire NAD+ is essential for biological processes such as metabolism et DNA repair, et its decline is associated with age-related diseas
Ginsénosides on Cancer et Related Clinical Studies Cancer is a leading cause of death globally, et its treatment often involves a combination of surgery, chemotherapy, et radiation therapy. These treatm
Ingénierie enzymatique couplée à la croissance par manipulation de la régénération des cofacteurs redox An increasingly wide range of chemicals are now being produced from renewable feedstocks through biotechnological means. Biopro
Supervision Policies for NMN in Japan, China, America, Australia et Canada The mainstream researches of NMN have been conducted since a decade years ago. The United States had already carried out its commerciali
Collections of Clinical Trails on NMN Oral Administation NMN, as one of NAD+ booster family critical members, become increasingly popular on the market in the filed of health pomoting. And to date, there are
Avec l'assouplissement des politiques de contrôle de l'épidémie dans le monde, les habitants de la Chine, de l'Inde, de la Malaisie, du Japon et de Singapour ont souffert d'une pénurie de médicaments à des degrés divers. Mais d'un autre côté, le type de médicaments disponibles
Attention! The Cambridge University Researchers Found Ursodeoxycholic Acid (UDCA) Can Prevent et Treat Covid-19 The International academic journal Nature published an article titled FXR inhibition may protect from SARS
Le 10 août 2021, des chercheurs de l'Université des sciences et technologies de Shanghai ont publié un article intitulé La supplémentation en NAD+ potentialise la fonction de destruction tumorale en sauvant la transcription NAMPT défectueuse médiée par TUBBY